Search Results for: Animal products treated for preservation
, camptothecins, hormones, anti-hormones, asparaginase, monoclonal antibodies and cytokines pharmacology views vinca alkaloids mitotic spindle poisons. vincristine is obtained from vinca rosea mechanism of action – dimeric form, bind tubulin to form tubulin complex – inhibit polymerization required for
spindle poison microtubules formed are not stable structurally, in absence of tubulin associated proteins, ctp leads to disruption, so known as mitotic spindle poisons. uses solid tumors ( breast, lung, ovarian, prostate, head/neck, esophagus, bladder, kaposi's sarcoma ) toxicity – hypersensitivity – treated...
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