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thus concentrates in bone, but genetic evidence has revealed that it does not play an important role in bone mineralization. in its uncarboxylated form, osteocalcin acts as a hormone in the body, signalling in the pancreas, fat, muscle, testes, and brain. [ ] in the pancreas, osteocalcin acts on beta cells
, causing beta cells in the pancreas to release more insulin . [ ] in fat cells , osteocalcin triggers the release of the hormone adiponectin , which increases sensitivity to insulin. [ ] in muscle, osteocalcin acts on myocytes to promote energy availability and utilization and in this manner favors...
https://en.wikipedia.org/wiki/Osteocalcin
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