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when this happens, glucose remains in the filtrate, leading to the osmotic retention of water in the urine. glucosuria causes a loss of hypotonic water and na+, leading to a hypertonic state with signs of volume depletion, such as dry mucosa, hypotension, tachycardia , and decreased turgor of the skin
"characterization of the antihypertensive effect of a thiazide diuretic in angiotensin ii-induced hypertension". journal of hypertension. ( ): – . doi : / - - . pmid . ^ drug monitor – diuretics archived january , , at the wayback machine ^ shankaran s, liang kc, ilagan n, fleischmann l (april )....
https://en.wikipedia.org/wiki/Diuretic