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distribution data from a phase study in patients with severe vwd receiving or iu/kg vwf:rco rvwf (n= ) (nct ; ethics committee approval and patients' informed consent were obtained). multimer pk profiles were derived through scaling the proportion of s, m, and l/ul multimers by total vwf antigen (vwf:ag) levels
, calculated as vwf:ag x vwf:s, vwf:ag x vwf:m and vwf:ag x vwf:l, respectively. results: disposition kinetics of vwf:ag x vwf:s, vwf:ag x vwf:m and vwf:ag x vwf:l were best described by two-compartment models. endogenous levels were accounted for as a constant background. pk model predictions showed...
https://abstracts.isth.org/abstract/investigating-the-relationship-between-vwf-multimeric-pattern-and-vwf-rco-activity-through-population-pk-modeling-in-patients-with-severe-vwd-treated-with-recombinant-vwf/
fair share, and to secure its conservation for the benefit of future generations. the management of water as an essential resource belongs in the public domain. water management must be organised and supervised by the public authority under the responsibility of elected representatives at all local levels
running the day-to-day activities of the association and for the implementation of its strategy. the general assembly is the main decision-making body of ape and is composed of all members of ape. it is convened at least once a year. the management board represents the association at all institutional levels...
https://www.aquapublica.eu/about
from dedicated producer programs to the industry's broadest ingredient portfolio, cargill is the right partner to help grow and protect brands by delivering non-gmo products to consumers. more some cargill products are only approved for use in certain geographies, end uses, and/or at certain usage levels
. it is the customer's responsibility to determine, for a particular geography, that (i) the cargill product, its use and usage levels, (ii) the customer's product and its use, and (iii) any claims made about the customer's product, all comply with applicable laws and regulations. twitter facebook linkedin...
https://www.cargill.com/food-beverage/na-foodbev-products
was implemented to assess the inhibitory effect of thr- on the migration of human umbilical vein endothelial cells (huvecs) and an ex vivo mouse choroidal explant model was used to evaluate the effect of thr- on blood vessel outgrowth. in addition, the anti-angiogenic potential of different dose levels
the single-digit nanomolar range, including, but not limited to, αvβ (ic of ± . nm), αvβ (ic of ± . nm) and α β (ic of ± . nm). thr- potently attenuated the migration of huvecs in the oristm system (ic of ± nm) as well as ex vivo choroidal vessel sprouting (ic of ± nm). in corroboration, all dose levels...
https://www.oxurion.com/sites/default/files/Abstract%20Euretina%202018_THR-687_THU_final.pdf
distribution data from a phase study in patients with severe vwd receiving or iu/kg vwf:rco rvwf (n= ) (nct ; ethics committee approval and patients' informed consent were obtained). multimer pk profiles were derived through scaling the proportion of s, m, and l/ul multimers by total vwf antigen (vwf:ag) levels
, calculated as vwf:ag x vwf:s, vwf:ag x vwf:m and vwf:ag x vwf:l, respectively. results: disposition kinetics of vwf:ag x vwf:s, vwf:ag x vwf:m and vwf:ag x vwf:l were best described by two-compartment models. endogenous levels were accounted for as a constant background. pk model predictions showed...
https://abstracts.isth.org/abstract/investigating-the-relationship-between-vwf-multimeric-pattern-and-vwf-rco-activity-through-population-pk-modeling-in-patients-with-severe-vwd-treated-with-recombinant-vwf/
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