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allowing ions to pass across the cell membrane . ligand-gated ion channels (lics, lgic), also commonly referred to as ionotropic receptors, are a group of transmembrane ion-channel proteins which open to allow ions such as na+ , k+ , ca + , and/or cl− to pass through the membrane in response to the binding
a depolarization , for an excitatory receptor response, or a hyperpolarization , for an inhibitory response. these receptor proteins are typically composed of at least two different domains: a transmembrane domain which includes the ion pore, and an extracellular domain which includes the ligand binding...
https://en.wikipedia.org/wiki/Ligand-gated_ion_channel