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considered to be insulin sparing. chen z ( ), zhou l ( ), kim sh ( ), yin j ( ). in various experiments using several biological cell models primed for insulin resistance, berberine demonstrated the ability to up-regulate insulin receptor (insr) expression, thereby positively identifying insr as a primary
biological target of berberine. zang h ( ) wang yx ( ) the insr-up-regulating and glucoselowering activities of berberine has also been investigated in humans. a study involving a variety of human cell lines including cem, hct- , sw , ht , t, and hepatitis b virus-transfected human liver cells showed...
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