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variation in the levels of gh and igf- in the circulation include an individual's genetic make-up, the time of day, age, sex, exercise status, stress levels, nutrition level, body mass index (bmi), disease state, race, estrogen status, and xenobiotic intake. [ ] [ ] [ ] igf- has an involvement in regulating
neural development including neurogenesis , myelination , synaptogenesis , and dendritic branching and neuroprotection after neuronal damage. increased serum levels of igf-i in children have been associated with higher iq . [ ] igf- shapes the development of the cochlea through controlling apoptosis...
https://en.wikipedia.org/wiki/Insulin-like_growth_factor
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